Neurontin and its newer, more powerful version, Lyrica, are widely used for unapproved indications that are a flagrant direct danger to the public. These most successful drugs were approved for use even though the FDA had no idea what they actually did in the brain. A new shocking study shows that they block the formation of new brain synapses1, drastically reducing the potential for rejuvenating brain plasticity – which means that these drugs cause brain decline faster than any substance known to mankind
The problem of these drugs is aggravated by their blatant illegal marketing. Neurontin was approved by the FDA for epilepsy in 1994. The drug was subjected to massive illegal promotion outside the indications that cost Warner-Lambert $ 430 million (the first great good for off-label promotion). The drug is now owned by Pfizer. Pfizer also owns Lyrica, a super-potent version of Neurontin. It has been approved by the FDA for various types of pain and fibromyalgia. Lyrica is one of four drugs that a Pfizer subsidiary markets illegally, resulting in a $ 2.3 million deal against Pfizer.
Even though the marketing of these drugs has been heavily fined, they continue to rack up billions in sales off-label uses. Doctors use them for all kinds of nervous problems because they are good at suppressing symptoms. However, such uses can no longer be justified because the actual mechanism of drugs is finally understood and they are creating a significant long-term reduction in nerve health.
Researchers in the previous study try to downplay the severity of the drugs by saying “adult neurons do not form many new synapses.” That simply is not true. The new science is showing that brain health during aging is based on the formation of new synapses. Even these researchers managed to question the common use of these drugs in pregnant women. How is a fetus supposed to produce new nerve cells when the mother is taking a drug that blocks them?
These are the kind of situations, the FDA must be everywhere. As usual, the FDA is sitting around reflecting on a Lyrica suicide warning, while its off-label uses include bipolar disorder and migraine headaches. you are likely to spin your thumbs for the next decade on the subject brain damage by the FDA. Consumer Alert.